A novel and practical asymmetric synthesis of dapoxetine hydrochloride.

ABSTRACT: A novel and practical asymmetric synthesis of dapoxetine hydrochloride by using the chiral auxiliary (S)-tert-butanesulfinamide was explored. The synthesis was concise, mild, and easy to perform. The overall yield and stereoselectivity were excellent.

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC4685759 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature