Cultured Cortical Neurons Can Perform Blind Source Separation According to the Free-Energy Principle.

ABSTRACT: Blind source separation is the computation underlying the cocktail party effect--a partygoer can distinguish a particular talker's voice from the ambient noise. Early studies indicated that the brain might use blind source separation as a signal processing strategy for sensory perception and numerous mathematical models have been proposed; however, it remains unclear how the neural networks extract particular sources from a complex mixture of inputs. We discovered that neurons in cultures of dissociated rat cortical cells could learn to represent particular sources while filtering out other signals. Specifically, the distinct classes of neurons in the culture learned to respond to the distinct sources after repeating training stimulation. Moreover, the neural network structures changed to

SUBMITTER: Isomura T 

PROVIDER: S-EPMC4686348 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature