Comparison of Post-injection Site Pain Between Technetium Sulfur Colloid and Technetium Tilmanocept in Breast Cancer Patients Undergoing Sentinel Lymph Node Biopsy.

ABSTRACT:

Background

No prior studies have examined injection pain associated with Technetium-99m Tilmanocept (TcTM).

Methods

This was a randomized, double-blinded study comparing postinjection site pain between filtered Technetium Sulfur Colloid (fTcSC) and TcTM in breast cancer lymphoscintigraphy. Pain was evaluated with a visual analogue scale (VAS) (0-100 mm) and the short-form McGill Pain Questionnaire (SF-MPQ). The primary endpoint was mean difference in VAS scores at 1-min postinjection between fTcSC and TcTM. Secondary endpoints included a comparison of SF-MPQ scores between the groups at 5 min postinjection and construction of a linear mixed effects model to evaluate the changes in pain during the 5-min postinjection period.

Results

Fifty-two patients underwent injecti

SUBMITTER: Unkart JT 

PROVIDER: S-EPMC4686557 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature