An overview of recommendations and translational milestones for genomic tests in cancer.

ABSTRACT:

Purpose

To understand the translational trajectory of genomic tests in cancer screening, diagnosis, prognosis, and treatment, we reviewed tests that have been assessed by recommendation and guideline developers.

Methods

For each test, we marked translational milestones by determining when the genomic association with cancer was first discovered and studied in patients, and when a health application for a specified clinical use was successfully demonstrated and approved or cleared by the US Food and Drug Administration. To identify recommendations and guidelines, we reviewed the websites of cancer, genomic, and general guideline developers and professional organizations. We searched the in vitro diagnostics database of the US Food and Drug Administration for information, and

SUBMITTER: Chang CQ 

PROVIDER: S-EPMC4686861 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature