Genetic differences among ethnic groups.

ABSTRACT:

Background

Many differences between different ethnic groups have been observed, such as skin color, eye color, height, susceptibility to some diseases, and response to certain drugs. However, the genetic bases of such differences have been under-investigated. Since the HapMap project, large-scale genotype data from Caucasian, African and Asian population samples have been available. The project found that these populations were located in different areas of the PCA (Principal Component Analysis) plot. However, as an unsupervised method, PCA does not measure the differences in each single nucleotide polymorphism (SNP) among populations.

Results

We applied an advanced mutual information-based feature selection method to detect associations between SNP status and ethnic groups

SUBMITTER: Huang T 

PROVIDER: S-EPMC4687076 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature