Paclitaxel Drug-Eluting Stents in Peripheral Arterial Disease: A Health Technology Assessment.

ABSTRACT:

Background

Peripheral arterial disease is a condition in which atherosclerotic plaques partially or completely block blood flow to the legs. Although percutaneous transluminal angioplasty and metallic stenting have high immediate success rates in treating peripheral arterial disease, long-term patency and restenosis rates in long and complex lesions remain unsatisfactory.

Objective

The objective of this analysis was to evaluate the clinical effectiveness, safety, cost-effectiveness and budget impact of Zilver paclitaxel self-expanding drug-eluting stents for the treatment of de novo or restenotic lesions in above-the-knee peripheral arterial disease.

Data sources

Literature searches were performed using Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citat

SUBMITTER: Health Quality Ontario 

PROVIDER: S-EPMC4688325 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature