Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial.

ABSTRACT:

Study question

Can treatment of the symptoms of uncomplicated urinary tract infection (UTI) with ibuprofen reduce the rate of antibiotic prescriptions without a significant increase in symptoms, recurrences, or complications?

Methods

Women aged 18-65 with typical symptoms of UTI and without risk factors or complications were recruited in 42 German general practices and randomly assigned to treatment with a single dose of fosfomycin 3 g (n=246; 243 analysed) or ibuprofen 3 × 400 mg (n=248; 241 analysed) for three days (and the respective placebo dummies in both groups). In both groups additional antibiotic treatment was subsequently prescribed as necessary for persistent, worsening, or recurrent symptoms. The primary endpoints were the number of all courses of antibiotic trea

SUBMITTER: Gagyor I 

PROVIDER: S-EPMC4688879 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature