BMI changes in adolescents treated with bupropion SR for smoking cessation.

ABSTRACT:

Objective

Adolescent overweight and obesity and smoking continue to be very important health challenges because of their lasting effects on overall health. Weight gain after smoking cessation is a barrier to quitting as well as a negative consequence to health. This study reports changes in the body mass index (BMI) z-scores of adolescent smokers participating in a dose-ranging clinical trial of bupropion SR (150 mg/day and 300 mg/day) for smoking cessation.

Methods

A total of N = 296 adolescent smokers (placebo n = 100, 150 mg/day n = 101, 300 mg/day n = 95) with a BMI z-score of 0.5 (sd: 1.4), 0.5 (sd: 1.3), and 0.5 (sd: 1.2) in the placebo, 150 mg/day, and 300 mg/day groups, respectively, were followed for 6 months.

Results

Adolescents in the 300 mg/day group had a

SUBMITTER: Floden L 

PROVIDER: S-EPMC4688900 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature