Subthalamic nucleus deep brain stimulation for Parkinson's disease: evidence for effectiveness and limitations from 12 years' experience.

ABSTRACT:

Objective

To present the result and experience of subthalamic nucleus deep brain stimulation for Parkinson's disease.

Design

Case series.

Setting

Prince of Wales Hospital, Hong Kong.

Patients

A cohort of patients with Parkinson's disease received subthalamic nucleus deep brain stimulation from September 1998 to January 2010. Patient assessment data before and after the operation were collected prospectively.

Results

Forty-one patients (21 male and 20 female) with Parkinson's disease underwent bilateral subthalamic nucleus deep brain stimulation and were followed up for a median interval of 12 months. For the whole group, the mean improvements of Unified Parkinson's Disease Rating Scale (UPDRS) parts II and III were 32.5% and 31.5%, respectively (P<0.001)

SUBMITTER: Movement Disorder Group 

PROVIDER: S-EPMC4691215 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature