Lateralization of cervical spinal cord activity during an isometric upper extremity motor task with functional magnetic resonance imaging.

ABSTRACT: The purpose of this study was to use an isometric upper extremity motor task to detect activity induced blood oxygen level dependent signal changes in the cervical spinal cord with functional magnetic resonance imaging. Eleven healthy volunteers performed six 5minute runs of an alternating left- and right-sided isometric wrist flexion task, during which images of the cervical spinal cord were acquired with a reduced field-of-view T2*-weighted gradient-echo echo-planar-imaging sequence. Spatial normalization to a standard spinal cord template was performed, and group average activation maps were generated in a mixed-effects analysis. The task activity significantly exceeded that of the control analyses. The activity was lateralized to the hemicord ipsilateral to the task and reliable across

SUBMITTER: Weber KA 

PROVIDER: S-EPMC4691376 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature