MicroRNA evolution, expression, and function during short germband development in Tribolium castaneum.

ABSTRACT: MicroRNAs are well-established players in the development of multicellular animals. Most of our understanding of microRNA function in arthropod development comes from studies in Drosophila. Despite their advantages as model systems, the long germband embryogenesis of fruit flies is an evolutionary derived state restricted to several holometabolous insect lineages. MicroRNA evolution and expression across development in animals exhibiting the ancestral and more widespread short germband mode of embryogenesis has not been characterized. We sequenced small RNA libraries of oocytes and successive intervals covering the embryonic development of the short germband model organism, Tribolium castaneum. We analyzed the evolution and temporal expression of the microRNA complement and sequenced libra

SUBMITTER: Ninova M 

PROVIDER: S-EPMC4691753 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature