Evolution of DNA-Binding Sites of a Floral Master Regulatory Transcription Factor.

ABSTRACT: Flower development is controlled by the action of key regulatory transcription factors of the MADS-domain family. The function of these factors appears to be highly conserved among species based on mutant phenotypes. However, the conservation of their downstream processes is much less well understood, mostly because the evolutionary turnover and variation of their DNA-binding sites (BSs) among plant species have not yet been experimentally determined. Here, we performed comparative ChIP (chromatin immunoprecipitation)-seq experiments of the MADS-domain transcription factor SEPALLATA3 (SEP3) in two closely related Arabidopsis species: Arabidopsis thaliana and A. lyrata which have very similar floral organ morphology. We found that BS conservation is associated with DNA sequence conservation

SUBMITTER: Muino JM 

PROVIDER: S-EPMC4693976 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature