Discontinuities in the endothelium of epiphyseal cartilage canals and relevance to joint disease in foals.

ABSTRACT: Cartilage canals have been shown to contain discontinuous blood vessels that enable circulating bacteria to bind to cartilage matrix, leading to vascular occlusion and associated pathological changes in pigs and chickens. It is also inconsistently reported that cartilage canals are surrounded by a cellular or acellular wall that may influence whether bacterial binding can occur. It is not known whether equine cartilage canals contain discontinuous endothelium or are surrounded by a wall. This study aimed to examine whether there were discontinuities in the endothelium of cartilage canal vessels, and whether canals had a cellular or acellular wall, in the epiphyseal growth cartilage of foals. Epiphyseal growth cartilage from the proximal third of the medial trochlear ridge of the distal fem

SUBMITTER: Hellings IR 

PROVIDER: S-EPMC4694163 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature