Green tea catechins and their metabolites in human skin before and after exposure to ultraviolet radiation.

ABSTRACT: Dietary flavonoids may protect against sunburn inflammation in skin. Preliminary reports using less complete analysis suggest that certain catechins and their metabolites are found in skin biopsies and blister fluid after consumption of green tea; however, it is not known if they are affected by solar-simulated ultraviolet radiation (UVR) or whether conjugated forms, with consequently altered bioactivity, are present. The present study tested the hypothesis that UVR affects the catechin levels in the skin of healthy volunteers after consumption of green tea and how catechins in the plasma are related to their presence in skin tissue samples. In an open oral intervention study, 11 subjects consumed green tea and vitamin C supplements daily for 3months. Presupplementation and postsupplementa

SUBMITTER: Clarke KA 

PROVIDER: S-EPMC4694608 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature