Early visual processing for low spatial frequency fearful face is correlated with cortical volume in patients with schizophrenia.

ABSTRACT: Patients with schizophrenia present with dysfunction of the magnocellular pathway, which might impair their early visual processing. We explored the relationship between functional abnormality of early visual processing and brain volumetric changes in schizophrenia. Eighteen patients and 16 healthy controls underwent electroencephalographic recordings and high-resolution magnetic resonance imaging. During electroencephalographic recordings, participants passively viewed neutral or fearful faces with broad, high, or low spatial frequency characteristics. Voxel-based morphometry was performed to investigate brain volume correlates of visual processing deficits. Event related potential analysis suggested that patients with schizophrenia had relatively impaired P100 processing of low spatial f

SUBMITTER: Lee JS 

PROVIDER: S-EPMC4694689 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature