Treatment Outcomes in Stage I Lung Cancer: A Comparison of Surgery and Stereotactic Body Radiation Therapy.

ABSTRACT:

Introduction

The relative roles of surgery and stereotactic body radiation therapy in stage I non-small-cell lung cancer (NSCLC) are evolving particularly for marginally operable patients. Because there is limited prospective comparative data for these treatment modalities, we evaluated their relative use and outcomes at the population level using a national database.

Methods

Patient variables and treatment-related outcomes were abstracted for patients with clinical stage I NSCLC from the National Cancer Database. Patients receiving surgery were compared with those undergoing stereotactic body radiation therapy (SBRT) in exploratory unmatched and subsequent propensity matched analyses.

Results

Between 1998 and 2010, 117,618 patients underwent surgery or SBRT for clini

SUBMITTER: Puri V 

PROVIDER: S-EPMC4695298 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature