Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle.

ABSTRACT:

Background

Ectopic fat deposition in liver and skeletal muscle tissue is related to cardiovascular disease risk and is a common metabolic complication in obese children. We evaluated the hypotheses of ectopic fat in these organs could be diminished following 1 year of multidisciplinary care specialized in childhood obesity, and whether this reduction would associate with changes in other markers of metabolic function.

Methods

This observational longitudinal study evaluated 40 overweight children and adolescents enrolled in a multidisciplinary treatment protocol at the Children's Obesity Clinic, Holbæk, Denmark. The participants were assessed by anthropometry, fasting blood samples (HbA1c, glucose, insulin, lipids, and biochemical variables of liver function), and liver and m

SUBMITTER: Fonvig CE 

PROVIDER: S-EPMC4696236 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature