Lactobacilli with probiotic potential in the prairie vole (Microtus ochrogaster).

ABSTRACT:

Background

Recent research suggests integration of the intestinal microbiota in gut-brain communication which could lead to new approaches to treat neurological disorders. The highly social prairie voles are an excellent model system to study the effects of environmental factors on social behavior. For future studies on the role of probiotics in ameliorating disorders with social withdrawal symptoms, we report the characterization of intestinal Lactobacillus isolates with probiotic potential from voles.

Methods and results

30 bacterial strains were isolated from the vole intestine and found to be distinct but closely related to Lactobacillus johnsonii using 16S rRNA gene sequencing and Random Amplification of Polymorphic DNA fingerprinting. In vitro characterizations includi

SUBMITTER: Assefa S 

PROVIDER: S-EPMC4696317 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature