Depression and Oropharynx Cancer Outcome.

ABSTRACT:

Background

Studies have shown a modest relationship between depression and mortality in patients with cancer. Our study addressed methodological weaknesses in the literature by restricting the sample to patients with one cancer type, adjusting for factors known to affect outcome, and following up patients for a sufficient period.

Methods

We prospectively followed patients newly diagnosed with squamous cell oropharyngeal cancer from the start of radiation therapy until death or until date of last clinical visit. All patients were optimally treated with radiation and sometimes chemotherapy. After adjusting for tumor stage, treatment, comorbidities, smoking, excessive alcohol use, and demographic factors, we assessed the effects of baseline self-reported depression on overall s

SUBMITTER: Shinn EH 

PROVIDER: S-EPMC4696911 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature