Risk Factors Associated With Incident Cerebral Microbleeds According to Location in Older People: The Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study.

ABSTRACT:

Importance

The spatial distribution of cerebral microbleeds (CMBs), which are asymptomatic precursors of intracerebral hemorrhage, reflects specific underlying microvascular abnormalities of cerebral amyloid angiopathy (lobar structures) and hypertensive vasculopathy (deep brain structures). Relatively little is known about the occurrence of and modifiable risk factors for developing CMBs, especially in a lobar location, in the general population of older people.

Objective

To investigate whether lifestyle and lipid factors predict new CMBs in relation to their anatomic location.

Design, setting, and participants

We enrolled 2635 individuals aged 66 to 93 years from the population-based Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study in a brain imaging stud

SUBMITTER: Ding J 

PROVIDER: S-EPMC4698002 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature