Relation between dietary fat intake type and serum fatty acid status in children with cystic fibrosis.

ABSTRACT:

Background and objective

Children with cystic fibrosis (CF) and pancreatic insufficiency (PI) are at risk for fatty acid (FA) abnormalities and essential FA deficiency, with low linoleic acid (LA) and docosahexaenoic acid (DHA) concentrations and abnormal triene:tetraene (T:T) and arachidonic acid (AA):DHA ratios. The aim of the article was to determine whether type of dietary fat predicted serum LA, DHA, T:T, and AA:DHA ratios in subjects with CF and PI as compared to an unaffected comparison group.

Methods

Serum FA concentrations were assessed by capillary gas-liquid chromatography (mol%) and dietary intake by 7-day weighed food records; the 3-day coefficient of fat absorption was calculated. Total energy intake was expressed in kilocalories.

Results

A total of 65 s

SUBMITTER: Maqbool A 

PROVIDER: S-EPMC4699309 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature