Impact of prolonged assisted ventilation on diaphragmatic efficiency: NAVA versus PSV.

ABSTRACT:

Background

Prolonged controlled mechanical ventilation depresses diaphragmatic efficiency. Assisted modes of ventilation should improve it. We assessed the impact of pressure support ventilation versus neurally adjusted ventilator assist on diaphragmatic efficiency.

Method

Patients previously ventilated with controlled mechanical ventilation for 72 hours or more were randomized to be ventilated for 48 hours with pressure support ventilation (n =12) or neurally adjusted ventilatory assist (n = 13). Neuro-ventilatory efficiency (tidal volume/diaphragmatic electrical activity) and neuro-mechanical efficiency (pressure generated against the occluded airways/diaphragmatic electrical activity) were measured during three spontaneous breathing trials (0, 24 and 48 hours). Breathing

SUBMITTER: Di Mussi R 

PROVIDER: S-EPMC4700777 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature