Can Emotional and Behavioral Dysregulation in Youth Be Decoded from Functional Neuroimaging?

ABSTRACT:

Introduction

High comorbidity among pediatric disorders characterized by behavioral and emotional dysregulation poses problems for diagnosis and treatment, and suggests that these disorders may be better conceptualized as dimensions of abnormal behaviors. Furthermore, identifying neuroimaging biomarkers related to dimensional measures of behavior may provide targets to guide individualized treatment. We aimed to use functional neuroimaging and pattern regression techniques to determine whether patterns of brain activity could accurately decode individual-level severity on a dimensional scale measuring behavioural and emotional dysregulation at two different time points.

Methods

A sample of fifty-seven youth (mean age: 14.5 years; 32 males) was selected from a multi-site stud

SUBMITTER: Portugal LC 

PROVIDER: S-EPMC4701457 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature