The Mechanism of Reflection Type Reentry: A Simulation Study.

ABSTRACT:

Introduction

Reflection is a special type of reentry in which an electrical wave front travels in a forward direction through tissue that is then re-excited by a wave front that propagates backward. This type of reentry has been studied computationally in 1-dimensional fibers and verified experimentally. Different hypotheses explaining reflected reentry have been proposed based on the structure and heterogeneity of the tissue properties, but the mechanism remains uncertain.

Methods and results

We used the bidomain model to represent cardiac tissue and the Luo-Rudy model to describe the active membrane properties. We consider an ischemic region in a volume of ventricular myocardium. Our results show that a slow depolarization in the ischemic border zone caused by electrotonic

SUBMITTER: Kandel SM 

PROVIDER: S-EPMC4701638 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature