Treatment for mild cognitive impairment: a systematic review and meta-analysis.

ABSTRACT:

Background

The effectiveness of treatments for mild cognitive impairment is uncertain. The aim of this review was to evaluate the effectiveness and harms of treatment for mild cognitive impairment in adults 65 years of age and older.

Methods

We searched MEDLINE, Embase and Cochrane Central (December 2012-December 2014); citations from 2 systematic reviews were considered for inclusion. We included randomized controlled trials involving community-dwelling adults aged 65 years and older with a diagnosis of mild cognitive impairment. Studies reporting on cognition, function, behaviour, global status, mortality and adverse events for treatment with pharmacologic and nonpharmacologic interventions were included.

Results

Seventeen studies were included. Cholinesterase inhib

SUBMITTER: Fitzpatrick-Lewis D 

PROVIDER: S-EPMC4701654 | biostudies-literature | 2015 Oct-Dec

REPOSITORIES: biostudies-literature