Omega-3 Fatty Acid Supplementation Lowers Serum FSH in Normal Weight But Not Obese Women.

ABSTRACT:

Context

Dietary omega-3 fatty acids delay ovarian aging and promote oocyte quality in mice.

Objective

To test whether dietary supplementation with omega-3 polyunsaturated fatty acids (PUFA) modulates reproductive hormones in reproductive-age women.

Design

Prospective interventional study.

Setting

Academic center.

Participants

Fifteen obese and 12 normal-weight (NW) eumenorrheic women, ages 28-34 years.

Intervention

Two frequent blood-sampling studies were performed before and after 1 month of omega-3 PUFA supplementation with 4 g of eicosapentaenoic acid and docosahexaenoic acid daily.

Main outcome measures

Serum LH and FSH (basal and after GnRH stimulation).

Results

The ratio of omega-6 to omega-3 PUFA was significantly reduced in p

SUBMITTER: Al-Safi ZA 

PROVIDER: S-EPMC4701838 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature