Rhodamine analogues for molecular ruler applications.

ABSTRACT: A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally.

SUBMITTER: Chu YH 

PROVIDER: S-EPMC4702047 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature