Evaluation of Neurocognition in Youth with CKD Using a Novel Computerized Neurocognitive Battery.

ABSTRACT:

Background and objectives

Neurocognitive problems in CKD are well documented; time-efficient methods are needed to assess neurocognition in this population. We performed the first study of the efficient 1-hour Penn Computerized Neurocognitive Battery (CNB) in children and young adults with CKD.

Design, setting, participants, & measurements

We administered the Penn CNB cross-sectionally to individuals aged 8-25 years with stage 2-5 CKD (n=92, enrolled from three academic nephrology practices from 2011 to 2014) and matched healthy controls (n=69). We analyzed results from 12 tests in four domains: executive control, episodic memory, complex cognition, and social cognition. All tests measure accuracy and speed; we converted raw scores to age-specific z-scores on the basis of Ph

SUBMITTER: Hartung EA 

PROVIDER: S-EPMC4702221 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature