Is Anti-Mullerian Hormone Associated With Fecundability? Findings From the EAGeR Trial.

ABSTRACT:

Objective

The objective of the study was to evaluate whether anti-Müllerian hormone (AMH) is associated with fecundability among women with proven fecundity and a history of pregnancy loss.

Design

This was a prospective cohort study within a multicenter, block-randomized, double-blind, placebo-controlled clinical trial ( clinicaltrials.gov , number NCT00467363).

Setting

The study was conducted at four US medical centers (2006-2012).

Participants

Participating women were aged 18-40 years, with a history of one to two pregnancy losses who were actively attempting pregnancy.

Main outcome measures

Time to human chorionic gonadotropin detected and clinical pregnancy were assessed using Cox proportional hazard regression models to estimate fecundability odds r

SUBMITTER: Zarek SM 

PROVIDER: S-EPMC4702454 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature