Impact of Phosphorus-Based Food Additives on Bone and Mineral Metabolism.

ABSTRACT:

Context

Phosphorus-based food additives can substantially increase total phosphorus intake per day, but the effect of these additives on endocrine factors regulating bone and mineral metabolism is unclear.

Objective

This study aimed to examine the effect of phosphorus additives on markers of bone and mineral metabolism. Design and Setting, and Participants: This was a feeding study of 10 healthy individuals fed a diet providing ∼1000 mg of phosphorus/d using foods known to be free of phosphorus additives for 1 week (low-additive diet), immediately followed by a diet containing identical food items; however, the foods contained phosphorus additives (additive-enhanced diet). Parallel studies were conducted in animals fed low- (0.2%) and high- (1.8%) phosphorus diets for 5 or 1

SUBMITTER: Gutierrez OM 

PROVIDER: S-EPMC4702463 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature