Meta-Analysis on the Correlation Between APOM rs805296 Polymorphism and Risk of Coronary Artery Disease.

ABSTRACT:

Background

The present meta-analysis aimed to summarize the inconsistent findings on the association of apolipoprotein M gene (ApoM) rs805296 polymorphism with the risk of coronary artery disease (CAD), and to obtain a more authentic result about this topic.

Material/methods

A total of 7 available articles were identified through electronic databases--PubMed, EMBASE, and Chinese National Knowledge Infrastructure (CNKI)--and their useful data were carefully extracted. The relationship between ApoM rs805296 polymorphism and CAD risk was assessed by odds ratios (ORs) and corresponding 95% confidence intervals (95% CIs), which were calculated using the fixed- or random-effects model, according to the degree of heterogeneity. Hardy-Weinberg equilibrium test, sensitivity test, and

SUBMITTER: Sun H 

PROVIDER: S-EPMC4702609 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature