DbMAE: the database of autosomal monoallelic expression.

ABSTRACT: Recently, data on 'random' autosomal monoallelic expression has become available for the entire genome in multiple human and mouse tissues and cell types, creating a need for better access and dissemination. The database of autosomal monoallelic expression (dbMAE; https://mae.hms.harvard.edu) incorporates data from multiple recent reports of genome-wide analyses. These include transcriptome-wide analyses of allelic imbalance in clonal cell populations based on sequence polymorphisms, as well as indirect identification, based on a specific chromatin signature present in MAE gene bodies. Currently, dbMAE contains transcriptome-wide chromatin identification calls for 8 human and 21 mouse tissues, and describes over 16 000 murine and ∼ 700 human cases of directly measured biased expression, co

SUBMITTER: Savova V 

PROVIDER: S-EPMC4702807 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature