Gut Microbiome Diversity among Cheyenne and Arapaho Individuals from Western Oklahoma.

ABSTRACT: Existing studies characterizing gut microbiome variation in the United States suffer from population ascertainment biases, with individuals of American Indian ancestry being among the most underrepresented. Here, we describe the first gut microbiome diversity study of an American Indian community. We partnered with the Cheyenne and Arapaho (C&A), federally recognized American Indian tribes in Oklahoma, and compared gut microbiome diversity and metabolic function of C&A participants to individuals of non-native ancestry in Oklahoma (NNIs). While the C&A and NNI participants share microbiome features common to industrialized populations, the C&A participants had taxonomic profiles characterized by a reduced abundance of the anti-inflammatory bacterial genus Faecalibacterium, along with a fec

SUBMITTER: Sankaranarayanan K 

PROVIDER: S-EPMC4703035 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature