Treating hypertension in hemodialysis improves symptoms seemingly unrelated to volume excess.

ABSTRACT:

Background

Among hemodialysis patients, probing dry weight is an effective strategy for improving control of hypertension. Whether controlling hypertension improves or worsens symptoms among such patients remains unclear. The purpose of the study was to develop a tool to evaluate symptoms and examine the relationship of the change in these symptoms with blood pressure (BP) control.

Methods

Among patients participating in the Hemodialysis Patients Treated with Atenolol or Lisinopril (HDPAL) randomized controlled trial, a confirmatory factor analysis (CFA) was performed to establish the relationship between symptoms and organ systems. Next, the change in symptom scores pertaining to organ systems was analyzed using a mixed model. Finally, the independent effect of lowering hom

SUBMITTER: Agarwal R 

PROVIDER: S-EPMC4703050 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature