Intraoperative Steroid Use and Outcomes Following the Norwood Procedure: An Analysis of the Pediatric Heart Network's Public Database.

ABSTRACT:

Objective

Data supporting the use of perioperative steroids during cardiac surgery are conflicting, and most pediatric studies have been limited by small sample sizes and/or diverse cardiac diagnoses. The objective of this study was to determine if intraoperative steroid administration improved outcomes following the Norwood procedure.

Design

A retrospective analysis was performed on the 549 neonates who underwent a Norwood procedure in the publicly available datasets from the Pediatric Heart Network's Single Ventricle Reconstruction trial. Groups were compared to determine if outcomes differed between intraoperative steroid recipients (n = 498, 91%) and nonrecipients (n = 51, 9%).

Setting

Fifteen North American centers.

Subjects

Infants enrolled in the Single

SUBMITTER: Elhoff JJ 

PROVIDER: S-EPMC4703451 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature