Making pharmacogenomic-based prescribing alerts more effective: A scenario-based pilot study with physicians.

ABSTRACT: To facilitate personalized drug dosing (PDD), this pilot study explored the communication effectiveness and clinical impact of using a prototype clinical decision support (CDS) system embedded in an electronic health record (EHR) to deliver pharmacogenomic (PGx) information to physicians. We employed a conceptual framework and measurement model to access the impact of physician characteristics (previous experience, awareness, relative advantage, perceived usefulness), technology characteristics (methods of implementation-semi-active/active, actionability-low/high) and a task characteristic (drug prescribed) on communication effectiveness (usefulness, confidence in prescribing decision), and clinical impact (uptake, prescribing intent, change in drug dosing). Physicians performed prescribin

SUBMITTER: Overby CL 

PROVIDER: S-EPMC4704108 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature