The neurotranscriptome of the Aedes aegypti mosquito.

ABSTRACT:

Background

A complete genome sequence and the advent of genome editing open up non-traditional model organisms to mechanistic genetic studies. The mosquito Aedes aegypti is an important vector of infectious diseases such as dengue, chikungunya, and yellow fever and has a large and complex genome, which has slowed annotation efforts. We used comprehensive transcriptomic analysis of adult gene expression to improve the genome annotation and to provide a detailed tissue-specific catalogue of neural gene expression at different adult behavioral states.

Results

We carried out deep RNA sequencing across all major peripheral male and female sensory tissues, the brain and (female) ovary. Furthermore, we examined gene expression across three important phases of the female reproductiv

SUBMITTER: Matthews BJ 

PROVIDER: S-EPMC4704297 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature