Polymorphisms of two loci at the oxytocin receptor gene in populations of Africa, Asia and South Europe.

ABSTRACT:

Background

The oxytocin (OT) system is known to be implicated in the regulation of complex social behavior, particularly empathy and parenting. The goal of this study was to estimate the gender and population differences in polymorphisms of two oxytocin receptor gene SNPs, rs53576 and rs2254298, in four populations.

Results

These data were compared with each other and with 14 samples from the corresponding regions retrieved from the 1000 Genomes database. Low level of heterozygosity was observed for both SNPs in all populations in this study (rs53576: Catalonian, Hobs = 0.413; Hadza, Hobs = 0.556; sr2254698: Khanty-Mansi, Hobs = 0.250; Datoga, Hobs = 0.550). The amount of variance due to regional variability was almost equal for both SNPs (rs53576: FRT = 0.086, rs2554298: FR

SUBMITTER: Butovskaya PR 

PROVIDER: S-EPMC4704389 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature