Physician perspectives of CYP2C19 and clopidogrel drug-gene interaction active clinical decision support alerts.

ABSTRACT:

Objective

To determine if physicians find clinical decision support alerts for pharmacogenomic drug-gene interactions useful and assess their perceptions of usability aspects that impact usefulness.

Materials and methods

52 physicians participated in an online simulation and questionnaire involving a prototype alert for the clopidogrel and CYP2C19 drug-gene interaction.

Results

Only 4% of participants stated they would override the alert. 92% agreed that the alerts were useful. 87% found the visual interface appropriate, 91% felt the timing of the alert was appropriate and 75% were unfamiliar with the specific drug-gene interaction. 80% of providers preferred the ability to order the recommended medication within the alert. Qualitative responses suggested that supplem

SUBMITTER: Nishimura AA 

PROVIDER: S-EPMC4704682 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature