Crystal structure of N-{4-[(6-chloro-pyridin-3-yl)meth-oxy]phen-yl}-2,6-di-fluoro-benzamide.

ABSTRACT: In the title compound, C19H13ClF2N2O2, the conformation of the N-H bond in the amide segment is anti to the C=O bond. The mol-ecule is not planar, with dihedral angles between the central benzene ring and the outer benzene and pyridyl rings of 73.35 (7) and 81.26 (6)°, respectively. A weak intra-molecular C-H⋯O hydrogen bond occurs. In the crystal, N-H⋯N, C-H⋯O and C-H⋯F hydrogen bonds lead to the formation of dimers. The N-H⋯N inversion dimers are linked by π-π contacts between adjacent pyridine rings [centroid-centroid = 3.8541 (12) Å] and C-H⋯π inter-actions. These contacts combine to stack the mol-ecules along the a axis.

SUBMITTER: Liang Y 

PROVIDER: S-EPMC4704742 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature