The LuxS Based Quorum Sensing Governs Lactose Induced Biofilm Formation by Bacillus subtilis.

ABSTRACT: Bacillus species present a major concern in the dairy industry as they can form biofilms in pipelines and on surfaces of equipment and machinery used in the entire line of production. These biofilms represent a continuous hygienic problem and can lead to serious economic losses due to food spoilage and equipment impairment. Biofilm formation by Bacillus subtilis is apparently dependent on LuxS quorum sensing (QS) by Autoinducer-2 (AI-2). However, the link between sensing environmental cues and AI-2 induced biofilm formation remains largely unknown. The aim of this study is to investigate the role of lactose, the primary sugar in milk, on biofilm formation by B. subtilis and its possible link to QS processes. Our phenotypic analysis shows that lactose induces formation of biofilm bundles as

SUBMITTER: Duanis-Assaf D 

PROVIDER: S-EPMC4705240 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature