Designing an Internationally Accessible Web-Based Questionnaire to Discover Risk Factors for Amyotrophic Lateral Sclerosis: A Case-Control Study.

ABSTRACT:

Background

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with a typical survival of three to five years. Epidemiological studies using paper-based questionnaires in individual countries or continents have failed to find widely accepted risk factors for the disease. The advantages of online versus paper-based questionnaires have been extensively reviewed, but few online epidemiological studies into human neurodegenerative diseases have so far been undertaken.

Objective

To design a Web-based questionnaire to identify environmental risk factors for ALS and enable international comparisons of these risk factors.

Methods

A Web-based epidemiological questionnaire for ALS has been developed based on experience gained from administering a prev

SUBMITTER: Parkin Kullmann JA 

PROVIDER: S-EPMC4705359 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature