A Probabilistic Atlas of Diffuse WHO Grade II Glioma Locations in the Brain.

ABSTRACT: Diffuse WHO grade II gliomas are diffusively infiltrative brain tumors characterized by an unavoidable anaplastic transformation. Their management is strongly dependent on their location in the brain due to interactions with functional regions and potential differences in molecular biology. In this paper, we present the construction of a probabilistic atlas mapping the preferential locations of diffuse WHO grade II gliomas in the brain. This is carried out through a sparse graph whose nodes correspond to clusters of tumors clustered together based on their spatial proximity. The interest of such an atlas is illustrated via two applications. The first one correlates tumor location with the patient's age via a statistical analysis, highlighting the interest of the atlas for studying the orig

SUBMITTER: Parisot S 

PROVIDER: S-EPMC4709135 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature