Identification of genomic variants putatively targeted by selection during dog domestication.

ABSTRACT:

Background

Dogs [Canis lupus familiaris] were the first animal species to be domesticated and continue to occupy an important place in human societies. Recent studies have begun to reveal when and where dog domestication occurred. While much progress has been made in identifying the genetic basis of phenotypic differences between dog breeds we still know relatively little about the genetic changes underlying the phenotypes that differentiate all dogs from their wild progenitors, wolves [Canis lupus]. In particular, dogs generally show reduced aggression and fear towards humans compared to wolves. Therefore, selection for tameness was likely a necessary prerequisite for dog domestication. With the increasing availability of whole-genome sequence data it is possible to try and direct

SUBMITTER: Cagan A 

PROVIDER: S-EPMC4710014 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature