Inhibition of Attention for Affective Material: Contributions by HOMER1 Gene Variation.

ABSTRACT: Failure to inhibit attention to irrelevant affective information has been linked to depression and rumination. However, few studies have investigated the biological bases of this process. Variation in the HOMER1 gene was identified in a genome-wide association study as associated with major depressive disorder and is associated with executive functioning inefficiency. Several studies have linked variation in the BDNF gene with emotional and cognitive processes such as rumination. The current study examined the association between these two auspicious genetic variants and inhibition of attention for affective information. In Study 1, 60 psychiatrically healthy community participants completed a negative affective priming task with positive and negative words. HOMER1 var

SUBMITTER: Wells TT 

PROVIDER: S-EPMC4711274 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature