Prostate cancer incidence in 43 populations worldwide: An analysis of time trends overall and by age group.

ABSTRACT: Prostate cancer is a significant public health burden and a major cause of morbidity and mortality among men worldwide. Analyzing geographic patterns and temporal trends may help identify high-risk populations, suggest the degree of PSA testing, and provide clues to etiology. We used incidence data available from the International Agency for Research on Cancer (IARC) and certain cancer registries for 43 populations across five continents during a median period of 24 years. Trends in overall prostate cancer rates showed five distinct patterns ranging from generally monotonic increases to peaking of rates followed by declines, which coincide somewhat with changes in the prevalence of PSA testing. Trends in age-specific rates generally mirrored those in the overall rates, with several notable

SUBMITTER: Zhou CK 

PROVIDER: S-EPMC4712103 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature