Genomic investigation reveals evolution and lifestyle adaptation of endophytic Staphylococcus epidermidis.

ABSTRACT: Staphylococcus epidermidis is a major human associated bacterium and also an emerging nosocomial pathogen. There are reports of its association to rodents, sheep and plants. However, comparative and evolutionary studies of ecologically diverse strains of S. epidermidis are lacking. Here, we report the whole genome sequences of four S. epidermidis strains isolated from surface sterilized rice seeds along with genome sequence of type strain. Phylogenomic analysis of rice endophytic S. epidermidis (RESE) with "type strain" unequivocally established their species identity. Whole genome based tree of 93 strains of S. epidermidis revealed RESE as distinct sub-lineage which is more related to rodent sub-lineage than to majority of human lineage strains. Furthermore, comparative genomics revealed

SUBMITTER: Chaudhry V 

PROVIDER: S-EPMC4713051 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature