Obesity and the Incidence of Upper Gastrointestinal Cancers: An Ecological Approach to Examine Differences across Age and Sex.

ABSTRACT:

Background

Esophageal and gastric cancers differ in their epidemiology but have several risk factors in common. The aim of this study was to assess age and sex differences in the burden of esophageal and gastric cancers in the context of the global obesity epidemic.

Methods

Data from 50 countries were obtained from Cancer Incidence in Five Continents Volume X and GLOBOCAN 2012. Age-specific and age-standardized incidence rates of esophageal adenocarcinoma and squamous cell carcinoma (ESCC), as well as cardia (CGC) and noncardia (NCGC) gastric cancer, were estimated. Countries were grouped and analyzed according to their obesity prevalence.

Results

A gradient across quartiles of obesity prevalence was found for esophageal adenocarcinoma, with the highest incidence rate

SUBMITTER: Arnold M 

PROVIDER: S-EPMC4713286 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature