In search of coding and non-coding regions of DNA sequences based on balanced estimation of diffusion entropy.

ABSTRACT: Identification of coding regions in DNA sequences remains challenging. Various methods have been proposed, but these are limited by species-dependence and the need for adequate training sets. The elements in DNA coding regions are known to be distributed in a quasi-random way, while those in non-coding regions have typical similar structures. For short sequences, these statistical characteristics cannot be extracted correctly and cannot even be detected. This paper introduces a new way to solve the problem: balanced estimation of diffusion entropy (BEDE).

SUBMITTER: Zhang J 

PROVIDER: S-EPMC4713410 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature