Evaluation of the Pulmonary Toxicity of Ambient Particulate Matter From Camp Victory, Iraq.

ABSTRACT: Anecdotal reports in the press and epidemiological studies suggest that deployment to Iraq and Afghanistan may be associated with respiratory diseases and symptoms in U.S. military personnel and veterans. Exposures during military operations were complex, but virtually all service members were exposed to high levels of respirable, geogenic dust. Inhalation of other dusts has been shown to be associated with adverse health effects, but the pulmonary toxicity of ambient dust from Iraq has not been previously studied. The relative toxicity of Camp Victory dust was evaluated by comparing it to particulate matter from northern Kuwait, a standard U.S. urban dust, and crystalline silica using a single intratracheal instillation in rats. Lung histology, protein levels, and cell counts were evaluat

SUBMITTER: Porter KL 

PROVIDER: S-EPMC4714599 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature